Our Pipeline

Our Pipeline
With Promise

Portfolio In Development

EQRx has more than 10 programs in our portfolio of potential medicines, including both small molecules and biologics, with five clinical-stage programs, and several preclinical and drug engineering programs. We strive to create best-in-class medicines that can make a meaningful impact for patients.

In order to assemble our portfolio, our current clinical-stage assets were in-licensed from biopharma companies around the world. In addition, we have entered into multiple drug engineering collaborations with leading technology platform companies, including those with technology-enabled experimental platforms, machine-learning computational platforms, and physics-based computational platforms, to efficiently engineer molecules against well-specified targets for important chronic and life-threatening conditions.

Legend

Ongoing Trials

Planned Trials

Program Target

Aumolertinib
EGFR

EGFR-mutated metastatic or locally advanced NSCLC

Phase 3

Adjuvant therapy in EGFR-mutated
NSCLC

Phase 3

Lerociclib
CDK4/6

1L / 2L advanced
breast cancer

Phase 2

Metastatic endometrial cancer

Phase 3

Sugemalimab
PD-L1

1L metastatic NSCLC

Phase 3

Consolidation therapy in locally
advanced/unresectable NSCLC

Phase 3

Nofazinlimab
PD-1

Hepatocellular carcinoma

Phase 3

EQ121
JAK1

Immune-inflammatory
indications

Phase 2

The safety and efficacy of these investigational compounds have not been established. There is no guarantee that the outcome of these studies will result in approval by a regulatory authority.

This pipeline describes investigational assets as of 2/23/2023.

View our Expanded Access Policy.

Abbreviations: 1L = first-line; 2L = second-line; CDK4/6 = cyclin-dependent kinase 4 and 6; EGFR = epidermal growth factor receptor; ENKTL = extra-nodal natural killer/T-cell lymphoma; JAK1 = Janus kinase 1; NSCLC = non-small cell lung cancer; PD-1 = programmed-death-1; PD-L1 = programmed death ligand-1.

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MED-00110 | February 2023